Lotz started her career as a dancer, touring with Avril Lavigne and Lady Gaga, starring in music videos, including Lady Gaga’s. Lotz began her acting career in 2006, with a small role in the cheerleading film, Bring It On: All or Nothing (2006). She followed that up, in 2010, with a part in Law & Order: LA: Harbor City (2010) and a recurring role in the fourth season of the AMC drama, Mad Men(2007), as “Stephanie”, Anna Draper’s niece. In 2011, Lotz starred as “Officer Kirsten Landry”, one of the main characters in the MTV horror, black comedy mockumentary series, Death Valley (2011). Lotz performs all her own stunts on the show.
For her work in 2013’s The Machine, she received a 2013 BIFA Award nomination for Most Promising Newcomer.